The construction of Jurassic Park is based on the DNA in mosquitoes. Although DNA is said to be stable, it is not too stable (otherwise, where is the mutation). It is now estimated that the life span at room temperature is difficult to exceed the order of a million years, and the last dinosaur was 65 million years ago, while the Jurassic was 100 million years ago. There were several reports in the 1980s and 1990s that ancient DNA was extracted (the author of the original book must have been inspired by this), and later proved to be all modern DNA contamination.
Even if it is extracted, repair is a big problem. The idea of taking the DNA of other species in the film is good (the problem is also here, although I don’t understand why amphibians are involved), but unfortunately even most of the DNA of humans has not figured out the role, so dinosaurs are extinct creatures. The sequence explained clearly does not know the year of the monkey. Moreover, there is now a view that there is a dynamic network relationship between biological genes. In this way, even functionally equivalent components of different species are likely to be incompatible... Moreover, dinosaurs have no close relatives... (Resurrection of the Przewalski's wild horse The possibility seems to be higher, some close relatives)
After the repair, there is still a problem: DNA is not equal to cells. Even if you get a complete genome, what can you do without a cell environment, but just a bunch of large molecules... Want to inject dinosaur DNA into a crocodile egg? The naked DNA degrades immediately. There has been some progress in artificial nuclei. It is estimated that a complete nuclear envelope can be made. However, according to the current cloning technology, the success rate of homologous nuclear transplantation is extremely low due to the problem of recoding (fortunately, the Japanese guy’s stem cell research helped this) , Xenotransplantation is bound to be more troublesome.
Finally, we got the recombinant diploid cells of dinosaurs. What can we do if we can develop... Originally, development was initiated by maternal mRNA. Can crocodile mRNA initiate dinosaur nuclei?
Therefore, in the foreseeable future, there will be no Jurassic Park...sigh.
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