- The film is dedicated to presenting the most realistic experience of space travel. The director described it as a mixture of "Apocalypse Now" and "2001: A Space Odyssey", and was influenced by the author of "Heart of Darkness" Joseph Connard.
- When Roy walked out of the meeting room, the wall of honor displayed photos and introductions of the meritorious astronauts, including Roy's father. In addition to him, other meritorious astronauts came from reality, including Apollo 11 astronauts Buzz Aldrin and Michael Collins; the first female astronaut to command a space mission, Irene Collins; the first not to be Bruce McCandres II, the astronaut on a rope space walk, and so on.
- In order to achieve the purpose of shooting in a narrow space, the scene had to be set twice during shooting, because the crew must have both a horizontal version and a vertical version of the same scene. On several occasions, Brad Pitt was hung 30 feet in the air so that the camera could take pictures of him when hung from an elevation angle. It looked as if he was weightless, but the shooting was very laborious.
- The English name of the film is "Ad Astra", which means "overcoming difficulties and sailing to the stars" in Latin, which implies the goal and determination to explore interstellar space.
- In reality, Voyager 2 took 12 years to arrive at Neptune, while the manned spacecraft in "Interstellar Exploration" took 79 days to reach Neptune from Mars.
- The Virgin Atlantic flight from the earth to the moon in the movie also exists in real life, and this company also has a plan for commercial space travel.
- When Roy became an adult (Brad Pitt), it was not NASA that led the space exploration, but the US Space Command. In reality, this organization was established in 1985 and disbanded in 2002, and again in 2019. Recovered again.
Ad Astra behind the scenes gags
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Roy McBride: Captain, I have a small oxygen leak in my suit, I'm just gonna check my patch.
Captain Lawrence Tanner: Have fun back there. We'll let you know if we spot any ETs.
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H. Clifford McBride: Home?
Roy McBride: Yep.
H. Clifford McBride: This is home. This is a one way voyage my son. You're talking about Earth? There was never anything for me there. I never cared about you, or your mother... or any of your small ideas. For 30 years... I've been breathing this air, eating this food... enduring these hardships... and I never once thought about home.
Roy McBride: I know, Dad.
H. Clifford McBride: I knew this would widow your mother... and orphan you... but I found my destiny. So, I abandoned my son.
Roy McBride: I still love you, Dad. I'm taking you back.
H. Clifford McBride: Hmm... I have work to do. I have infinite work to do. I must find intelligent life.
Roy McBride: It's time to go. We don't have much time. Come on.