- The film is the fourth film of Martin Scorsese and Leonardo DiCaprio's collaboration. "The Closed Island" also maintains the story length that Martin Scorsese has filmed since 2002. The film must be a record starring Leonardo DiCaprio.
- When Paramount made the film, the first director was David Fincher, and the starring role was Brad Pitt. However, the two later withdrew from "The Curious Case of Benjamin Button" due to the filming of the film "The Curious Case of Benjamin Button". "The shooting plan.
- Before deciding that Mark Ruffalo will play the role of Chuck, Martin Scorsese also considered the role of Robert Downey Jr. and Josh Brolin.
- Leonardo hates mice, but there was a scene where he stayed with mice during the filming. When Leonardo's hand touched a mouse, he was so scared that he backed away.
Shutter Island behind the scenes gags
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Dr. John Cawley: [re: Rachel] We don't know how she got out of her room. It was locked from the outside. And the only window's barred. It's as if she evaporated, straight through the walls.
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Dr. John Cawley: [examines Rachel's note] Ah, this is definitely Rachel's handwriting. I have no idea... what the "Law of Four" is, though.
Teddy Daniels: It's not a psychiatric term?
Dr. John Cawley: No, I'm afraid not.
Chuck Aule: [reads the note] "Who is 67?" Fucked if I know.
Dr. John Cawley: I have to say that's quite close to my clinical conclusion.